It belongs to a group of medications called sulfonamide antibiotics. Evidence exists that the use of SSD may place patients at increased a risk of developing neutropenia, erythema multiforme, crystalluria, and methemoglobinemia. Other methods are better and more cost effective. It works by killing or preventing the growth of bacteria in the wound. The traditional idea that SSD cream is the first-line treatment for minor burn wounds is archaic. SILVER SULFADIAZINE (SIL ver sul fa DYE a zeen) prevents and treats infections in burn wounds. The available evidence suggests that honey dressings promote better wound healing than silver sulfadiazine for burns.īurn Dressing Healing time Honey Meta-analysis Silver sulfadiazine.Ĭopyright © 2016 Elsevier Ltd and ISBI. And pharmacists with time to talk, even on nights and weekends. Based on moderate quality evidence there was a statistically significant difference between the two groups, favoring honey in healing time (MD -5.76days, 95% CI -8.14 to -3.39) and the proportions of infected wounds rendered sterile (RR 2.59 95% CI 1.58-2.88). Description: Silver sulfadiazine antimicrobial against gram-positive and gram-negative bacteria as well as some yeasts and fungi.The silver salt acts mainly on the cell wall and membrane and inhibits the essential enzymes, leading to bacterial death. Am I eligible for the Rx Advantage Card and how much does silver sulfadiazine cost without. The primary endpoints considered were wound healing time and the number of infected wounds rendered sterile. State Medicaid programs may cover the full cost of your medication. The quality of the selected trials was assessed using the Cochrane Risk of Bias Assessment Tool. Relevant databases for randomized controlled trials (RCTs) of honey compared with silver sulfadiazine (SSD) were searched. The objective of this review was to assess the effects of honey compared with silver dressings on the healing of burn wounds. Evidence from animal studies and trials suggests that honey may accelerate wound healing.
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